SNP Detail For rs4511180
1.Mapping Information
Human SNP ID rs4511180
Human chromosome chr1
Human SNP position 202180311
Pig chromosome chr10
Pig SNP position 28725900
2.Annotation Information
PubMed ID25456346
JournalPsychoneuroendocrinology
Linkwww.ncbi.nlm.nih.gov/pubmed/25456346
StudyGenomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.
Disease/TraitPost-traumatic stress disorder
Initial sample940 European, Hispanic, Native American, African American, East Asian and other ancestry cases, 2,554 European, Hispanic, Native American, African American, East Asian and other ancestry trauma-exposed controls
Replication sample313 European ancestry cases, 178 European ancestry trauma-exposed controls
Region1q32.1
Chromosome idchr1
Chromosome position202180311
Reported genePTPRV
Mapped genePTPRVP
Upstream gene id
Downstream gene id
SNP gene ids148713
Upstream gene distance
Downstream gene distance
SNP risk allelers4511180-A
SNPsrs4511180
Merged0
SNP id current4511180
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.268
P value0.0000008
Pvalue mlog6.09691001300805
P value text(African American)
Or beta4.178
%95 Ci[3.62-4.74]
PlatformIllumina [21693469] (imputed)
CNVN
Mapped traitpost-traumatic stress disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001358
Study accessionGCST002681