Human SNP ID | rs4506565 |
---|---|
Human chromosome | chr10 |
Human SNP position | 112996282 |
Pig chromosome | chr14 |
Pig SNP position | 134626197 |
PubMed ID | 17554300 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/17554300 |
Study | Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. |
Disease/Trait | Type 2 diabetes |
Initial sample | 1,924 European ancestry cases, 2,938 European ancestry controls |
Replication sample | (see Zeggini 2007) |
Region | 10q25.2 |
Chromosome id | chr10 |
Chromosome position | 112996282 |
Reported gene | TCF7L2 |
Mapped gene | TCF7L2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6934 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4506565-T |
SNPs | rs4506565 |
Merged | 0 |
SNP id current | 4506565 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.32 |
P value | 0.000000000005 |
Pvalue mlog | 11.3010299956639 |
P value text | |
Or beta | 1.36 |
%95 Ci | [1.20-1.54] |
Platform | Affymetrix [469557] |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST000047 |
PubMed ID | 20081858 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20081858 |
Study | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. |
Disease/Trait | Fasting glucose-related traits |
Initial sample | up to 46,186 European ancestry individuals |
Replication sample | up to 76,558 European ancestry individuals |
Region | 10q25.2 |
Chromosome id | chr10 |
Chromosome position | 112996282 |
Reported gene | TCF7L2 |
Mapped gene | TCF7L2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6934 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4506565-T |
SNPs | rs4506565 |
Merged | 0 |
SNP id current | 4506565 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.31 |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | (FPG) |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | fasting blood glucose measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004465 |
Study accession | GCST000568 |