SNP Detail For rs4466877
1.Mapping Information
Human SNP ID rs4466877
Human chromosome chr11
Human SNP position 114516380
Pig chromosome chr9
Pig SNP position 46810940
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region11q23.2
Chromosome idchr11
Chromosome position114516380
Reported geneNR
Mapped geneLOC101926945
Upstream gene id
Downstream gene id
SNP gene ids101926945
Upstream gene distance
Downstream gene distance
SNP risk allelers4466877-G
SNPsrs4466877
Merged0
SNP id current4466877
Contextupstream_gene_variant
Intergenic0
Allele frequency0.880799535011136
P value0.0000009
Pvalue mlog6.04575749056067
P value text(IGP32)
Or beta0.2413
%95 Ci[0.15-0.34] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848