Human SNP ID | rs445114 |
---|---|
Human chromosome | chr8 |
Human SNP position | 127310936 |
Pig chromosome | chr4 |
Pig SNP position | 13065208 |
PubMed ID | 21743057 |
---|---|
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21743057 |
Study | Genome-wide association study identifies new prostate cancer susceptibility loci. |
Disease/Trait | Prostate cancer |
Initial sample | 2,782 European ancestry cases, 4,458 European ancestry controls |
Replication sample | 7,358 European ancestry cases, 6,732 European ancestry controls |
Region | 8q24.21 |
Chromosome id | chr8 |
Chromosome position | 127310936 |
Reported gene | intergenic |
Mapped gene | CASC21, CASC8 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 103021164, 727677 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs445114-T |
SNPs | rs445114 |
Merged | 0 |
SNP id current | 445114 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000005 |
Pvalue mlog | 6.30102999566398 |
P value text | |
Or beta | 1.22 |
%95 Ci | [1.12-1.32] |
Platform | Illumina [571243] |
CNV | N |
Mapped trait | prostate carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001663 |
Study accession | GCST001147 |
PubMed ID | 19767754 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19767754 |
Study | Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. |
Disease/Trait | Prostate cancer |
Initial sample | Up to 1,968 European ancestry cases, 35,382 European ancestry controls |
Replication sample | Up to 11,806 European ancestry cases, 12,387 European ancestry controls |
Region | 8q24.21 |
Chromosome id | chr8 |
Chromosome position | 127310936 |
Reported gene | intergenic |
Mapped gene | CASC21, CASC8 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 103021164, 727677 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs445114-T |
SNPs | rs445114 |
Merged | 0 |
SNP id current | 445114 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.64 |
P value | 0.0000000005 |
Pvalue mlog | 9.30102999566398 |
P value text | |
Or beta | 1.14 |
%95 Ci | [1.10-1.19] |
Platform | Illumina [310520] |
CNV | N |
Mapped trait | prostate carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001663 |
Study accession | GCST000489 |
PubMed ID | 22219177 |
Journal | Carcinogenesis |
Link | www.ncbi.nlm.nih.gov/pubmed/22219177 |
Study | A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. |
Disease/Trait | Prostate cancer (gene x gene interaction) |
Initial sample | 4,723 European ancestry cases, 4,792 European ancestry controls |
Replication sample | NA |
Region | 22q12.1 x 8q24.21 |
Chromosome id | chr22 x 8 |
Chromosome position | 27456222 x 127310936 |
Reported gene | MN1 x NR |
Mapped gene | LOC105372980 - LOC105372981 x CASC21, CASC8 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6005451-? x rs445114-? |
SNPs | rs6005451 x rs445114 |
Merged | 0 |
SNP id current | |
Context | downstream_gene_variant x intron_variant |
Intergenic | |
Allele frequency | NR |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | |
Or beta | 1.42 |
%95 Ci | [1.22-1.65] |
Platform | Affymetrix, Illumina [1117531] (imputed) |
CNV | N |
Mapped trait | prostate carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001663 |
Study accession | GCST001370 |