SNP Detail For rs4410790
1.Mapping Information
Human SNP ID rs4410790
Human chromosome chr7
Human SNP position 17244953
Pig chromosome chr9
Pig SNP position 95346030
2.Annotation Information
PubMed ID21490707
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21490707
StudyGenome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
Disease/TraitCaffeine consumption
Initial sample47,431 European ancestry individuals
Replication sampleNA
Region7p21.1
Chromosome idchr7
Chromosome position17244953
Reported geneAHR
Mapped geneLOC105375170 - LOC101927609
Upstream gene id105375170
Downstream gene id101927609
SNP gene ids
Upstream gene distance223337
Downstream gene distance34991
SNP risk allelers4410790-T
SNPsrs4410790
Merged0
SNP id current4410790
Contextintergenic_variant
Intergenic1
Allele frequency0.38
P value2E-19
Pvalue mlog18.698970004336
P value text
Or beta0.15
%95 Ci[0.11-0.19] mg/day decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitcoffee consumption
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004330
Study accessionGCST001032
PubMed ID25288136
JournalMol Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/25288136
StudyGenome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
Disease/TraitCoffee consumption (cups per day)
Initial sample91,462 European ancestry individuals
Replication sample30,062 European ancestry individuals, 7,964 African American individuals
Region7p21.1
Chromosome idchr7
Chromosome position17244953
Reported geneAHR
Mapped geneLOC105375170 - LOC101927609
Upstream gene id105375170
Downstream gene id101927609
SNP gene ids
Upstream gene distance223337
Downstream gene distance34991
SNP risk allelers4410790-T
SNPsrs4410790
Merged0
SNP id current4410790
Contextintergenic_variant
Intergenic1
Allele frequency0.37
P value0.00000000000000003
Pvalue mlog16.5228787452803
P value text
Or beta0.1
%95 Ci[0.08-0.12] unit decrease
PlatformAffymetrix, Illumina [2373958] (imputed)
CNVN
Mapped traitcoffee consumption, cups of coffee per day measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004330, http://www.ebi.ac.uk/efo/EFO_0006782
Study accessionGCST002650