Human SNP ID | rs438475 |
---|---|
Human chromosome | chr6 |
Human SNP position | 32218468 |
Pig chromosome | chr7 |
Pig SNP position | 28070338 |
PubMed ID | 26503763 |
---|---|
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/26503763 |
Study | Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. |
Disease/Trait | Objective response to lithium treatment in bipolar disorder |
Initial sample | 323 European ancestry responder cases, 853 European ancestry non-responder cases |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32218468 |
Reported gene | NOTCH4 |
Mapped gene | NOTCH4 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4855 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs438475-A |
SNPs | rs438475 |
Merged | 0 |
SNP id current | 438475 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.12 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | |
Or beta | 2.04 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [> 8000000] (imputed) |
CNV | N |
Mapped trait | bipolar disorder, response to lithium ion |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000289, http://purl.obolibrary.org/obo/GO_0010226 |
Study accession | GCST003161 |