Human SNP ID | rs4373814 |
---|---|
Human chromosome | chr10 |
Human SNP position | 18131043 |
Pig chromosome | chr10 |
Pig SNP position | 49142784 |
PubMed ID | 21909115 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
Disease/Trait | Systolic blood pressure |
Initial sample | 69,395 European ancestry individuals |
Replication sample | Up to 133,361 European ancestry individuals |
Region | 10p12.33 |
Chromosome id | chr10 |
Chromosome position | 18131043 |
Reported gene | CACNB2 |
Mapped gene | SLC39A12 - CACNB2 |
Upstream gene id | 221074 |
Downstream gene id | 783 |
SNP gene ids | |
Upstream gene distance | 87751 |
Downstream gene distance | 9634 |
SNP risk allele | rs4373814-G |
SNPs | rs4373814 |
Merged | 0 |
SNP id current | 4373814 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.55 |
P value | 0.00000000005 |
Pvalue mlog | 10.3010299956639 |
P value text | |
Or beta | 0.373 |
%95 Ci | [NR] mmHg decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | systolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006335 |
Study accession | GCST001227 |
PubMed ID | 21909115 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
Disease/Trait | Diastolic blood pressure |
Initial sample | 69,395 European ancestry individuals |
Replication sample | Up to 133,361 European ancestry individuals |
Region | 10p12.33 |
Chromosome id | chr10 |
Chromosome position | 18131043 |
Reported gene | CACNB2 |
Mapped gene | SLC39A12 - CACNB2 |
Upstream gene id | 221074 |
Downstream gene id | 783 |
SNP gene ids | |
Upstream gene distance | 87751 |
Downstream gene distance | 9634 |
SNP risk allele | rs4373814-G |
SNPs | rs4373814 |
Merged | 0 |
SNP id current | 4373814 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.55 |
P value | 0.0000000004 |
Pvalue mlog | 9.39794000867203 |
P value text | |
Or beta | 0.218 |
%95 Ci | [NR] mmHg decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | diastolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
Study accession | GCST001228 |
PubMed ID | 21909115 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
Disease/Trait | Hypertension |
Initial sample | 69,395 European ancestry individuals |
Replication sample | Up to 133,361 European ancestry individuals |
Region | 10p12.33 |
Chromosome id | chr10 |
Chromosome position | 18131043 |
Reported gene | CACNB2 |
Mapped gene | SLC39A12 - CACNB2 |
Upstream gene id | 221074 |
Downstream gene id | 783 |
SNP gene ids | |
Upstream gene distance | 87751 |
Downstream gene distance | 9634 |
SNP risk allele | rs4373814-G |
SNPs | rs4373814 |
Merged | 0 |
SNP id current | 4373814 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.55 |
P value | 0.00000009 |
Pvalue mlog | 7.04575749056067 |
P value text | |
Or beta | 0.046 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | hypertension |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000537 |
Study accession | GCST001238 |