Human SNP ID | rs4320486 |
---|---|
Human chromosome | chr7 |
Human SNP position | 108003532 |
Pig chromosome | chr9 |
Pig SNP position | 118515109 |
PubMed ID | 24986923 |
---|---|
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24986923 |
Study | A genome-wide association study identifies susceptibility loci of silica related pneumoconiosis in Han Chinese. |
Disease/Trait | Pneumoconiosis in silica exposure |
Initial sample | 202 Han Chinese ancestry cases, 198 Han Chinese ancestry controls |
Replication sample | 490 Han Chinese ancestry cases, 541 Han Chinese ancestry controls |
Region | 7q31.1 |
Chromosome id | chr7 |
Chromosome position | 108003532 |
Reported gene | LAMB1 |
Mapped gene | LAMB1 - LAMB4 |
Upstream gene id | 3912 |
Downstream gene id | 22798 |
SNP gene ids | |
Upstream gene distance | 173 |
Downstream gene distance | 454 |
SNP risk allele | rs4320486-C |
SNPs | rs4320486 |
Merged | 0 |
SNP id current | 4320486 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.755 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | |
Or beta | 1.69 |
%95 Ci | [1.35-2.13] |
Platform | Illumina [710999] (imputed) |
CNV | N |
Mapped trait | pneumoconiosis, response to silica exposure |
Mapped trait URI | http://www.orpha.net/ORDO/Orphanet_182098, http://www.ebi.ac.uk/efo/EFO_0005853 |
Study accession | GCST002515 |