SNP Detail For rs4272
1.Mapping Information
Human SNP ID rs4272
Human chromosome chr7
Human SNP position 92607515
Pig chromosome chr9
Pig SNP position 79242431
2.Annotation Information
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region7q21.2
Chromosome idchr7
Chromosome position92607515
Reported geneCDK6
Mapped geneCDK6
Upstream gene id
Downstream gene id
SNP gene ids1021
Upstream gene distance
Downstream gene distance
SNP risk allelers4272-G
SNPsrs4272
Merged0
SNP id current4272
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.19
P value0.000000005
Pvalue mlog8.30102999566398
P value text
Or beta1.1
%95 Ci[1.06-1.13]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region7q21.2
Chromosome idchr7
Chromosome position92607515
Reported geneCDK6
Mapped geneCDK6
Upstream gene id
Downstream gene id
SNP gene ids1021
Upstream gene distance
Downstream gene distance
SNP risk allelers4272-G
SNPsrs4272
Merged0
SNP id current4272
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.21
P value0.00000001
Pvalue mlog8
P value text(EA)
Or beta1.1
%95 Ci[1.07-1.14]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318