Human SNP ID | rs4253311 |
---|---|
Human chromosome | chr4 |
Human SNP position | 186253529 |
Pig chromosome | chr15 |
Pig SNP position | 53935670 |
PubMed ID | 24816252 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24816252 |
Study | An atlas of genetic influences on human blood metabolites. |
Disease/Trait | Blood metabolite levels |
Initial sample | 7,824 European ancestry individuals |
Replication sample | NA |
Region | 4q35.2 |
Chromosome id | chr4 |
Chromosome position | 186253529 |
Reported gene | KLKB1 |
Mapped gene | KLKB1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3818 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4253311-A |
SNPs | rs4253311 |
Merged | 0 |
SNP id current | 4253311 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.49 |
P value | 4E-48 |
Pvalue mlog | 47.397940008672 |
P value text | (bradykinin, des-arg(9)) |
Or beta | 0.141 |
%95 Ci | [0.12-0.16] unit decrease |
Platform | Affymetrix, Illumina [2100000] (imputed) |
CNV | N |
Mapped trait | blood metabolite measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005664 |
Study accession | GCST002443 |
PubMed ID | 25477429 |
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25477429 |
Study | Genome-Wide Meta-Analyses of Plasma Renin Activity and Concentration Reveal Association with the Kininogen 1 and Prekallikrein Genes. |
Disease/Trait | Plasma renin activity levels |
Initial sample | 5,275 European ancestry individuals |
Replication sample | NA |
Region | 4q35.2 |
Chromosome id | chr4 |
Chromosome position | 186253529 |
Reported gene | KLKB1 |
Mapped gene | KLKB1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3818 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4253311-A |
SNPs | rs4253311 |
Merged | 0 |
SNP id current | 4253311 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000006 |
Pvalue mlog | 7.22184874961635 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | plasma renin activity measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006828 |
Study accession | GCST002714 |