Human SNP ID | rs419076 |
---|---|
Human chromosome | chr3 |
Human SNP position | 169383098 |
Pig chromosome | chr13 |
Pig SNP position | 116760605 |
PubMed ID | 21909110 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21909110 |
Study | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. |
Disease/Trait | Blood pressure |
Initial sample | 74,064 European ancestry individuals |
Replication sample | 48,607 European ancestry individuals |
Region | 3q26.2 |
Chromosome id | chr3 |
Chromosome position | 169383098 |
Reported gene | MECOM |
Mapped gene | MECOM |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2122 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs419076-T |
SNPs | rs419076 |
Merged | 0 |
SNP id current | 419076 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.44 |
P value | 0.0000000000008 |
Pvalue mlog | 12.096910013008 |
P value text | (Mean Arterial Pressure) |
Or beta | 0.34 |
%95 Ci | [0.25-0.43] mmHg increase |
Platform | Affymetrix, Illumina, Perlegen [NR] (imputed) |
CNV | N |
Mapped trait | mean arterial pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006340 |
Study accession | GCST001236 |
PubMed ID | 21909115 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
Disease/Trait | Diastolic blood pressure |
Initial sample | 69,395 European ancestry individuals |
Replication sample | Up to 133,361 European ancestry individuals |
Region | 3q26.2 |
Chromosome id | chr3 |
Chromosome position | 169383098 |
Reported gene | MECOM |
Mapped gene | MECOM |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2122 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs419076-T |
SNPs | rs419076 |
Merged | 0 |
SNP id current | 419076 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 0.000000000002 |
Pvalue mlog | 11.698970004336 |
P value text | |
Or beta | 0.241 |
%95 Ci | [NR] mmHg increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | diastolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
Study accession | GCST001228 |
PubMed ID | 21909115 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21909115 |
Study | Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. |
Disease/Trait | Systolic blood pressure |
Initial sample | 69,395 European ancestry individuals |
Replication sample | Up to 133,361 European ancestry individuals |
Region | 3q26.2 |
Chromosome id | chr3 |
Chromosome position | 169383098 |
Reported gene | MECOM |
Mapped gene | MECOM |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2122 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs419076-T |
SNPs | rs419076 |
Merged | 0 |
SNP id current | 419076 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 0.0000000000002 |
Pvalue mlog | 12.698970004336 |
P value text | |
Or beta | 0.409 |
%95 Ci | [NR] mmHg increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | systolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006335 |
Study accession | GCST001227 |