SNP Detail For rs4149584
1.Mapping Information
Human SNP ID rs4149584
Human chromosome chr12
Human SNP position 6333477
Pig chromosome chr5
Pig SNP position 66788942
2.Annotation Information
PubMed ID19525953
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19525953
StudyMeta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
Disease/TraitMultiple sclerosis
Initial sample2,624 European ancestry cases, 7,220 European ancestry controls
Replication sample2,215 European ancestry cases, 2,116 European ancestry controls
Region12p13.31
Chromosome idchr12
Chromosome position6333477
Reported geneTNFRSF1A
Mapped geneTNFRSF1A
Upstream gene id
Downstream gene id
SNP gene ids7132
Upstream gene distance
Downstream gene distance
SNP risk allelers4149584-T
SNPsrs4149584
Merged0
SNP id current4149584
Contextmissense_variant
Intergenic0
Allele frequency0.022
P value0.000005
Pvalue mlog5.30102999566398
P value text
Or beta1.58
%95 Ci[1.15-2.17]
PlatformAffymetrix, Illumina [~ 2560000] (imputed)
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST000424