SNP Detail For rs41475954
1.Mapping Information
Human SNP ID rs41475954
Human chromosome chr18
Human SNP position 37505770
Pig chromosome chr6
Pig SNP position 114132975
2.Annotation Information
PubMed ID26053186
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26053186
StudyMercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
Disease/Trait3-hydroxypropylmercapturic acid levels in smokers
Initial sample362 African American current smoker individuals, 329 Native Hawaiian ancestry current smoker individuals, 438 European ancestry current smoker individuals, 449 Latino current smoker individuals, 704 Japanese ancestry current smoker individuals
Replication sampleNA
Region18q12.2
Chromosome idchr18
Chromosome position37505770
Reported geneNR
Mapped geneCELF4
Upstream gene id
Downstream gene id
SNP gene ids56853
Upstream gene distance
Downstream gene distance
SNP risk allelers41475954-?
SNPsrs41475954
Merged
SNP id current41475954
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000004
Pvalue mlog8.39794000867203
P value text(Japanese)
Or beta0.6178
%95 Ci[NR] unit decrease
PlatformIllumina [up to 11892802] (imputed)
CNVN
Mapped traitsmoking behavior, 3-hydroxypropylmercapturic acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007014
Study accessionGCST002956
PubMed ID26053186
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26053186
StudyMercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
Disease/Trait3-hydroxy-1-methylpropylmercapturic acid levels in smokers
Initial sample361 African American current smoker individuals, 329 Native Hawaiian ancestry current smoker individuals, 440 European ancestry current smoker individuals, 452 Latino current smoker individuals, 702 Japanese ancestry current smoker individuals
Replication sampleNA
Region18q12.2
Chromosome idchr18
Chromosome position37505770
Reported geneNR
Mapped geneCELF4
Upstream gene id
Downstream gene id
SNP gene ids56853
Upstream gene distance
Downstream gene distance
SNP risk allelers41475954-?
SNPsrs41475954
Merged
SNP id current41475954
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text(Japanese)
Or beta0.4614
%95 Ci[NR] unit decrease
PlatformIllumina [up to 11892802] (imputed)
CNVN
Mapped traitsmoking behavior, 3-hydroxy-1-methylpropylmercapturic acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007015
Study accessionGCST002957