SNP Detail For rs41314643
1.Mapping Information
Human SNP ID rs41314643
Human chromosome chr1
Human SNP position 183286773
Pig chromosome chr9
Pig SNP position 136837365
2.Annotation Information
PubMed ID25187353
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25187353
StudyClozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Disease/TraitClozapine-induced agranulocytosis
Initial sample161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls
Replication sampleNA
Region1q25.3
Chromosome idchr1
Chromosome position183286773
Reported geneLAMC1, LAMC2, NMNAT2
Mapped geneNMNAT2
Upstream gene id
Downstream gene id
SNP gene ids23057
Upstream gene distance
Downstream gene distance
SNP risk allelers41314643-C
SNPsrs41314643
Merged0
SNP id current41314643
Contextmissense_variant
Intergenic0
Allele frequency0.0159
P value0.000001
Pvalue mlog6
P value text
Or beta5.2714815
%95 Ci[4.6-5.95]
PlatformIllumina [8809853] (imputed)
CNVN
Mapped traitdrug-induced agranulocytosis, response to clozapine
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338
Study accessionGCST002595