Human SNP ID | rs41314643 |
---|---|
Human chromosome | chr1 |
Human SNP position | 183286773 |
Pig chromosome | chr9 |
Pig SNP position | 136837365 |
PubMed ID | 25187353 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25187353 |
Study | Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. |
Disease/Trait | Clozapine-induced agranulocytosis |
Initial sample | 161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls |
Replication sample | NA |
Region | 1q25.3 |
Chromosome id | chr1 |
Chromosome position | 183286773 |
Reported gene | LAMC1, LAMC2, NMNAT2 |
Mapped gene | NMNAT2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 23057 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs41314643-C |
SNPs | rs41314643 |
Merged | 0 |
SNP id current | 41314643 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.0159 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | |
Or beta | 5.2714815 |
%95 Ci | [4.6-5.95] |
Platform | Illumina [8809853] (imputed) |
CNV | N |
Mapped trait | drug-induced agranulocytosis, response to clozapine |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338 |
Study accession | GCST002595 |