Human SNP ID | rs4081724 |
---|---|
Human chromosome | chr19 |
Human SNP position | 33334040 |
Pig chromosome | chr6 |
Pig SNP position | 38661192 |
PubMed ID | 25673412 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 19q13.11 |
Chromosome id | chr19 |
Chromosome position | 33334040 |
Reported gene | CEBPA |
Mapped gene | LOC105372369 - AKR1B1P7 |
Upstream gene id | 105372369 |
Downstream gene id | 126242 |
SNP gene ids | |
Upstream gene distance | 10837 |
Downstream gene distance | 26086 |
SNP risk allele | rs4081724-G |
SNPs | rs4081724 |
Merged | 0 |
SNP id current | 4081724 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.8488 |
P value | 0.0000009 |
Pvalue mlog | 6.04575749056067 |
P value text | (EA, women) |
Or beta | 0.0327 |
%95 Ci | [0.02-0.046] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 19q13.11 |
Chromosome id | chr19 |
Chromosome position | 33334040 |
Reported gene | CEBPA |
Mapped gene | LOC105372369 - AKR1B1P7 |
Upstream gene id | 105372369 |
Downstream gene id | 126242 |
SNP gene ids | |
Upstream gene distance | 10837 |
Downstream gene distance | 26086 |
SNP risk allele | rs4081724-G |
SNPs | rs4081724 |
Merged | 0 |
SNP id current | 4081724 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.8522 |
P value | 0.0000001 |
Pvalue mlog | 7 |
P value text | (EA, men) |
Or beta | 0.0391 |
%95 Ci | [0.025-0.054] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 19q13.11 |
Chromosome id | chr19 |
Chromosome position | 33334040 |
Reported gene | CEBPA |
Mapped gene | LOC105372369 - AKR1B1P7 |
Upstream gene id | 105372369 |
Downstream gene id | 126242 |
SNP gene ids | |
Upstream gene distance | 10837 |
Downstream gene distance | 26086 |
SNP risk allele | rs4081724-G |
SNPs | rs4081724 |
Merged | 0 |
SNP id current | 4081724 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.8512 |
P value | 0.000000000007 |
Pvalue mlog | 11.1549019599857 |
P value text | (EA) |
Or beta | 0.0347 |
%95 Ci | [0.025-0.045] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 19q13.11 |
Chromosome id | chr19 |
Chromosome position | 33334040 |
Reported gene | CEBPA |
Mapped gene | LOC105372369 - AKR1B1P7 |
Upstream gene id | 105372369 |
Downstream gene id | 126242 |
SNP gene ids | |
Upstream gene distance | 10837 |
Downstream gene distance | 26086 |
SNP risk allele | rs4081724-G |
SNPs | rs4081724 |
Merged | 0 |
SNP id current | 4081724 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.8536 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | (men) |
Or beta | 0.0378 |
%95 Ci | [0.023-0.052] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 19q13.11 |
Chromosome id | chr19 |
Chromosome position | 33334040 |
Reported gene | CEBPA |
Mapped gene | LOC105372369 - AKR1B1P7 |
Upstream gene id | 105372369 |
Downstream gene id | 126242 |
SNP gene ids | |
Upstream gene distance | 10837 |
Downstream gene distance | 26086 |
SNP risk allele | rs4081724-G |
SNPs | rs4081724 |
Merged | 0 |
SNP id current | 4081724 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.8504 |
P value | 0.0000005 |
Pvalue mlog | 6.30102999566398 |
P value text | (women) |
Or beta | 0.0334 |
%95 Ci | [0.02-0.047] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 19q13.11 |
Chromosome id | chr19 |
Chromosome position | 33334040 |
Reported gene | CEBPA |
Mapped gene | LOC105372369 - AKR1B1P7 |
Upstream gene id | 105372369 |
Downstream gene id | 126242 |
SNP gene ids | |
Upstream gene distance | 10837 |
Downstream gene distance | 26086 |
SNP risk allele | rs4081724-G |
SNPs | rs4081724 |
Merged | 0 |
SNP id current | 4081724 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.8529 |
P value | 0.000000000005 |
Pvalue mlog | 11.3010299956639 |
P value text | |
Or beta | 0.0347 |
%95 Ci | [0.025-0.044] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |