Human SNP ID | rs4077408 |
---|---|
Human chromosome | chr1 |
Human SNP position | 210587100 |
Pig chromosome | chr9 |
Pig SNP position | 145457322 |
PubMed ID | 26516778 |
---|---|
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/26516778 |
Study | Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. |
Disease/Trait | Cardiovascular disease in hypertension (ACE inhibitor interaction) |
Initial sample | Up to 3,527 European ancestry individuals with cardiovascular disease, up to 11,848 European ancestry individuals without cardiovascular disease |
Replication sample | Up to 1,751 European ancestry individuals with cardiovascular disease, up to 1,267 African American ancestry individuals with cardiovascular disease, up to 2,874 African American ancestry individuals without cardiovascular disease |
Region | 1q32.2 |
Chromosome id | chr1 |
Chromosome position | 210587100 |
Reported gene | HHAT |
Mapped gene | HHAT |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 55733 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4077408-A |
SNPs | rs4077408 |
Merged | 0 |
SNP id current | 4077408 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.69 |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | (EA) |
Or beta | 0.25 |
%95 Ci | [NR] unit increase |
Platform | Affymetrix, Illumina [1892626] (imputed) |
CNV | N |
Mapped trait | hypertension, cardiovascular disease, response to angiotensin-converting enzyme inhibitor |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000537, http://www.ebi.ac.uk/efo/EFO_0000319, http://www.ebi.ac.uk/efo/EFO_0005325 |
Study accession | GCST003186 |