SNP Detail For rs4077408
1.Mapping Information
Human SNP ID rs4077408
Human chromosome chr1
Human SNP position 210587100
Pig chromosome chr9
Pig SNP position 145457322
2.Annotation Information
PubMed ID26516778
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26516778
StudyDrug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.
Disease/TraitCardiovascular disease in hypertension (ACE inhibitor interaction)
Initial sampleUp to 3,527 European ancestry individuals with cardiovascular disease, up to 11,848 European ancestry individuals without cardiovascular disease
Replication sampleUp to 1,751 European ancestry individuals with cardiovascular disease, up to 1,267 African American ancestry individuals with cardiovascular disease, up to 2,874 African American ancestry individuals without cardiovascular disease
Region1q32.2
Chromosome idchr1
Chromosome position210587100
Reported geneHHAT
Mapped geneHHAT
Upstream gene id
Downstream gene id
SNP gene ids55733
Upstream gene distance
Downstream gene distance
SNP risk allelers4077408-A
SNPsrs4077408
Merged0
SNP id current4077408
Contextintron_variant
Intergenic0
Allele frequency0.69
P value0.000008
Pvalue mlog5.09691001300805
P value text(EA)
Or beta0.25
%95 Ci[NR] unit increase
PlatformAffymetrix, Illumina [1892626] (imputed)
CNVN
Mapped traithypertension, cardiovascular disease, response to angiotensin-converting enzyme inhibitor
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000537, http://www.ebi.ac.uk/efo/EFO_0000319, http://www.ebi.ac.uk/efo/EFO_0005325
Study accessionGCST003186