Human SNP ID | rs404256 |
---|---|
Human chromosome | chr6 |
Human SNP position | 89948064 |
Pig chromosome | chr1 |
Pig SNP position | 64914652 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6q15 |
Chromosome id | chr6 |
Chromosome position | 89948064 |
Reported gene | BACH2 |
Mapped gene | BACH2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 60468 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs404256-C |
SNPs | rs404256 |
Merged | 0 |
SNP id current | 404256 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.55888563217352 |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (IGP44) |
Or beta | 0.1659 |
%95 Ci | [0.095-0.237] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6q15 |
Chromosome id | chr6 |
Chromosome position | 89948064 |
Reported gene | BACH2 |
Mapped gene | BACH2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 60468 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs404256-C |
SNPs | rs404256 |
Merged | 0 |
SNP id current | 404256 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.559129675122385 |
P value | 0.000000007 |
Pvalue mlog | 8.15490195998574 |
P value text | (IGP7) |
Or beta | 0.2094 |
%95 Ci | [0.14-0.28] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |