SNP Detail For rs3942852
1.Mapping Information
Human SNP ID rs3942852
Human chromosome chr11
Human SNP position 48093537
Pig chromosome chr2
Pig SNP position 15709456
2.Annotation Information
PubMed ID22076464
JournalLeukemia
Linkwww.ncbi.nlm.nih.gov/pubmed/22076464
StudyIdentification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
Disease/TraitAcute lymphoblastic leukemia (childhood)
Initial sample419 European ancestry ETV6-RUNX1 positive cases, 474 European ancestry controls
Replication sample951 European ancestry ETV6-RUNX1 positive cases, 326 European ancestry ETV6-RUNX1 negative cases, 3,061 European ancestry controls
Region11p11.2
Chromosome idchr11
Chromosome position48093537
Reported genePTPRJ
Mapped genePTPRJ
Upstream gene id
Downstream gene id
SNP gene ids5795
Upstream gene distance
Downstream gene distance
SNP risk allelers3942852-C
SNPsrs3942852
Merged0
SNP id current3942852
Contextintron_variant
Intergenic0
Allele frequency0.22
P value0.0000005
Pvalue mlog6.30102999566398
P value text(ETV6-RUNX1 positive, Northern European)
Or beta
%95 Ci
PlatformAffymetrix [355750]
CNVN
Mapped traitacute lymphoblastic leukemia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000220
Study accessionGCST001320
PubMed ID22076464
JournalLeukemia
Linkwww.ncbi.nlm.nih.gov/pubmed/22076464
StudyIdentification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
Disease/TraitAcute lymphoblastic leukemia (childhood)
Initial sample419 European ancestry ETV6-RUNX1 positive cases, 474 European ancestry controls
Replication sample951 European ancestry ETV6-RUNX1 positive cases, 326 European ancestry ETV6-RUNX1 negative cases, 3,061 European ancestry controls
Region11p11.2
Chromosome idchr11
Chromosome position48093537
Reported genePTPRJ
Mapped genePTPRJ
Upstream gene id
Downstream gene id
SNP gene ids5795
Upstream gene distance
Downstream gene distance
SNP risk allelers3942852-T
SNPsrs3942852
Merged0
SNP id current3942852
Contextintron_variant
Intergenic0
Allele frequency0.78
P value0.000001
Pvalue mlog6
P value text(ETV6-RUNX1 positive)
Or beta1.2987013
%95 Ci[1.12-1.47]
PlatformAffymetrix [355750]
CNVN
Mapped traitacute lymphoblastic leukemia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000220
Study accessionGCST001320