SNP Detail For rs3934007
1.Mapping Information
Human SNP ID rs3934007
Human chromosome chr11
Human SNP position 113668358
Pig chromosome chr9
Pig SNP position 46127065
2.Annotation Information
PubMed ID25338677
JournalGenes Immun
Linkwww.ncbi.nlm.nih.gov/pubmed/25338677
StudyGenetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.
Disease/TraitInterferon alpha levels in systemic lupus erythematosus
Initial sample88 European ancestry high interferon alpha cases, 322 European ancestry low interferon alpha cases
Replication sample715 European ancestry cases, 450 African American cases
Region11q23.2
Chromosome idchr11
Chromosome position113668358
Reported geneTMPRSS5, DRD2
Mapped geneLOC105369501 - TMPRSS5
Upstream gene id105369501
Downstream gene id80975
SNP gene ids
Upstream gene distance167620
Downstream gene distance19188
SNP risk allelers3934007-T
SNPsrs3934007
Merged0
SNP id current3934007
Contextregulatory_region_variant
Intergenic1
Allele frequencyNR
P value0.000003
Pvalue mlog5.52287874528033
P value text(EA)
Or beta1.55
%95 Ci[1.19-2.00]
PlatformIllumina [291943]
CNVN
Mapped traitinterferon alpha measurement, systemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006517, http://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST002666