Human SNP ID | rs3934007 |
---|---|
Human chromosome | chr11 |
Human SNP position | 113668358 |
Pig chromosome | chr9 |
Pig SNP position | 46127065 |
PubMed ID | 25338677 |
---|---|
Journal | Genes Immun |
Link | www.ncbi.nlm.nih.gov/pubmed/25338677 |
Study | Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus. |
Disease/Trait | Interferon alpha levels in systemic lupus erythematosus |
Initial sample | 88 European ancestry high interferon alpha cases, 322 European ancestry low interferon alpha cases |
Replication sample | 715 European ancestry cases, 450 African American cases |
Region | 11q23.2 |
Chromosome id | chr11 |
Chromosome position | 113668358 |
Reported gene | TMPRSS5, DRD2 |
Mapped gene | LOC105369501 - TMPRSS5 |
Upstream gene id | 105369501 |
Downstream gene id | 80975 |
SNP gene ids | |
Upstream gene distance | 167620 |
Downstream gene distance | 19188 |
SNP risk allele | rs3934007-T |
SNPs | rs3934007 |
Merged | 0 |
SNP id current | 3934007 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | (EA) |
Or beta | 1.55 |
%95 Ci | [1.19-2.00] |
Platform | Illumina [291943] |
CNV | N |
Mapped trait | interferon alpha measurement, systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006517, http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST002666 |