SNP Detail For rs3923113
1.Mapping Information
Human SNP ID rs3923113
Human chromosome chr2
Human SNP position 164645339
Pig chromosome chr15
Pig SNP position 79510716
2.Annotation Information
PubMed ID21874001
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21874001
StudyGenome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
Disease/TraitType 2 diabetes
Initial sample5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls
Replication sample13,170 South Asian ancestry cases, 25,398 South Asian ancestry controls
Region2q24.3
Chromosome idchr2
Chromosome position164645339
Reported geneGRB14
Mapped geneGRB14 - LOC101929615
Upstream gene id2888
Downstream gene id101929615
SNP gene ids
Upstream gene distance23489
Downstream gene distance8044
SNP risk allelers3923113-A
SNPsrs3923113
Merged0
SNP id current3923113
Contextintergenic_variant
Intergenic1
Allele frequency0.74
P value0.00000001
Pvalue mlog8
P value text
Or beta1.09
%95 Ci[1.06-1.13]
PlatformIllumina [568976]
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST001213
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region2q24.3
Chromosome idchr2
Chromosome position164645339
Reported geneGRB14
Mapped geneGRB14 - LOC101929615
Upstream gene id2888
Downstream gene id101929615
SNP gene ids
Upstream gene distance23489
Downstream gene distance8044
SNP risk allelers3923113-A
SNPsrs3923113
Merged0
SNP id current3923113
Contextintergenic_variant
Intergenic1
Allele frequency0.61
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta1.04
%95 Ci[1.00-1.09]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352