SNP Detail For rs3875149
1.Mapping Information
Human SNP ID rs3875149
Human chromosome chr19
Human SNP position 40854091
Pig chromosome chr6
Pig SNP position 44867765
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region19q13.2
Chromosome idchr19
Chromosome position40854091
Reported geneIntergenic
Mapped geneCYP2A6 - CYP2A7
Upstream gene id1548
Downstream gene id1549
SNP gene ids
Upstream gene distance3644
Downstream gene distance21348
SNP risk allelers3875149-A
SNPsrs3875149
Merged0
SNP id current3875149
Contextintron_variant
Intergenic1
Allele frequency0.386
P value0.0000006
Pvalue mlog6.22184874961635
P value text
Or beta0.061
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region19q13.2
Chromosome idchr19
Chromosome position40854091
Reported geneIntergenic
Mapped geneCYP2A6 - CYP2A7
Upstream gene id1548
Downstream gene id1549
SNP gene ids
Upstream gene distance3644
Downstream gene distance21348
SNP risk allelers3875149-A
SNPsrs3875149
Merged0
SNP id current3875149
Contextintron_variant
Intergenic1
Allele frequency0.388
P value0.00000006
Pvalue mlog7.22184874961635
P value text
Or beta0.013
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264