Human SNP ID | rs3865444 |
---|---|
Human chromosome | chr19 |
Human SNP position | 51224706 |
Pig chromosome | chr6 |
Pig SNP position | 51736911 |
PubMed ID | 21460841 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21460841 |
Study | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer__s disease. |
Disease/Trait | Alzheimer__s disease (late onset) |
Initial sample | 8,309 European ancestry cases, 7,366 European ancestry controls |
Replication sample | 10,523 European ancestry cases, 28,231 European ancestry controls |
Region | 19q13.41 |
Chromosome id | chr19 |
Chromosome position | 51224706 |
Reported gene | CD33 |
Mapped gene | CD33 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 945 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3865444-? |
SNPs | rs3865444 |
Merged | 0 |
SNP id current | 3865444 |
Context | upstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.7 |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | |
Or beta | 1.1 |
%95 Ci | [1.08-1.14] |
Platform | Affymetrix, Illumina [2324889] (imputed) |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST001026 |
PubMed ID | 24162737 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24162737 |
Study | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer__s disease. |
Disease/Trait | Alzheimer__s disease (late onset) |
Initial sample | 17,008 European ancestry cases, 37,154 European ancestry controls |
Replication sample | 8,572 European ancestry cases, 11,312 European ancestry controls |
Region | 19q13.41 |
Chromosome id | chr19 |
Chromosome position | 51224706 |
Reported gene | CD33 |
Mapped gene | CD33 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 945 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3865444-C |
SNPs | rs3865444 |
Merged | 0 |
SNP id current | 3865444 |
Context | upstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.693 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | |
Or beta | 1.06 |
%95 Ci | [1.04-1.1] |
Platform | Illumina [7055881] (imputed) |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST002245 |