SNP Detail For rs3851634
1.Mapping Information
Human SNP ID rs3851634
Human chromosome chr12
Human SNP position 106419124
Pig chromosome chr5
Pig SNP position 13985077
2.Annotation Information
PubMed ID26424050
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/26424050
StudyGenome-wide association study identifies multiple susceptibility loci for glioma.
Disease/TraitGlioma
Initial sample1,783 Northern European ancestry glioblastoma cases, 2,364 Northern European ancestry non-glioblastoma cases, 7,435 Northern European ancestry controls
Replication sample1,490 European ancestry cases, 1,723 European ancestry control
Region12q23.3
Chromosome idchr12
Chromosome position106419124
Reported genePOLR3B
Mapped genePOLR3B
Upstream gene id
Downstream gene id
SNP gene ids55703
Upstream gene distance
Downstream gene distance
SNP risk allelers3851634-T
SNPsrs3851634
Merged0
SNP id current3851634
Contextintron_variant
Intergenic0
Allele frequency0.7
P value0.0000004
Pvalue mlog6.39794000867203
P value text
Or beta1.15
%95 Ci[1.09-1.22]
PlatformIllumina [at least 8427548] (imputed)
CNVN
Mapped traitcentral nervous system cancer
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000326
Study accessionGCST003228
PubMed ID26424050
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/26424050
StudyGenome-wide association study identifies multiple susceptibility loci for glioma.
Disease/TraitGlioblastoma
Initial sample1,783 Northern European ancestry cases, 7,435 Northern European ancestry controls
Replication sampleup to 1,490 European ancestry cases, up to 1,723 European ancestry controls
Region12q23.3
Chromosome idchr12
Chromosome position106419124
Reported genePOLR3B
Mapped genePOLR3B
Upstream gene id
Downstream gene id
SNP gene ids55703
Upstream gene distance
Downstream gene distance
SNP risk allelers3851634-T
SNPsrs3851634
Merged0
SNP id current3851634
Contextintron_variant
Intergenic0
Allele frequency0.7
P value0.000000003
Pvalue mlog8.52287874528033
P value text
Or beta1.2345679
%95 Ci[1.15-1.32]
PlatformIllumina [at least 8427548] (imputed)
CNVN
Mapped traitglioblastoma multiforme
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000519
Study accessionGCST003220