Human SNP ID | rs3851179 |
---|---|
Human chromosome | chr11 |
Human SNP position | 86157598 |
Pig chromosome | chr9 |
Pig SNP position | 22265719 |
PubMed ID | 19734902 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19734902 |
Study | Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer__s disease. |
Disease/Trait | Alzheimer__s disease |
Initial sample | 3,941 European ancestry cases, 7,848 European ancestry controls |
Replication sample | 2,023 European ancestry cases, 2,340 European ancestry controls |
Region | 11q14.2 |
Chromosome id | chr11 |
Chromosome position | 86157598 |
Reported gene | PICALM |
Mapped gene | PICALM - FNTAP1 |
Upstream gene id | 8301 |
Downstream gene id | 283226 |
SNP gene ids | |
Upstream gene distance | 87717 |
Downstream gene distance | 37533 |
SNP risk allele | rs3851179-? |
SNPs | rs3851179 |
Merged | 0 |
SNP id current | 3851179 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.63 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | |
Or beta | 1.16 |
%95 Ci | [1.11-1.22] |
Platform | Illumina [529205] |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST000479 |
PubMed ID | 25778476 |
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/25778476 |
Study | A novel Alzheimer disease locus located near the gene encoding tau protein. |
Disease/Trait | Alzheimer__s disease in APOE e4- carriers |
Initial sample | 7,184 cases, 26,968 controls |
Replication sample | 718 European ancestry cases, 1,699 European ancestry controls |
Region | 11q14.2 |
Chromosome id | chr11 |
Chromosome position | 86157598 |
Reported gene | PICALM |
Mapped gene | PICALM - FNTAP1 |
Upstream gene id | 8301 |
Downstream gene id | 283226 |
SNP gene ids | |
Upstream gene distance | 87717 |
Downstream gene distance | 37533 |
SNP risk allele | rs3851179-C |
SNPs | rs3851179 |
Merged | 0 |
SNP id current | 3851179 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.65 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | |
Or beta | 1.1235955 |
%95 Ci | [1.06-1.18] |
Platform | NR [NR] |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST002817 |