SNP Detail For rs3825932
1.Mapping Information
Human SNP ID rs3825932
Human chromosome chr15
Human SNP position 78943104
Pig chromosome chr7
Pig SNP position 53642205
2.Annotation Information
PubMed ID18978792
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/18978792
StudyMeta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.
Disease/TraitType 1 diabetes
Initial sample3,561 European ancestry cases, 4,646 European ancestry controls
Replication sample6,225 European ancestry cases, 6,946 European ancestry controls, 3,064 European ancestry trios from 2,828 families
Region15q25.1
Chromosome idchr15
Chromosome position78943104
Reported geneCTSH
Mapped geneCTSH
Upstream gene id
Downstream gene id
SNP gene ids1512
Upstream gene distance
Downstream gene distance
SNP risk allelers3825932-T
SNPsrs3825932
Merged0
SNP id current3825932
Contextintron_variant
Intergenic0
Allele frequency0.68
P value0.000000000000003
Pvalue mlog14.5228787452803
P value text
Or beta1.16
%95 Ci[1.10-1.22]
PlatformAffymetrix [up to 335565]
CNVN
Mapped traittype I diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001359
Study accessionGCST000258
PubMed ID19430480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19430480
StudyGenome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Disease/TraitType 1 diabetes
Initial sample7,514 cases, 9,045 controls
Replication sample4,267 cases, 4,670 controls, 4,342 trios from 2,319 families
Region15q25.1
Chromosome idchr15
Chromosome position78943104
Reported geneCTSH
Mapped geneCTSH
Upstream gene id
Downstream gene id
SNP gene ids1512
Upstream gene distance
Downstream gene distance
SNP risk allelers3825932-?
SNPsrs3825932
Merged0
SNP id current3825932
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000008
Pvalue mlog7.09691001300805
P value text
Or beta
%95 Ci
PlatformAffymetrix, Illumina [841622] (imputed)
CNVN
Mapped traittype I diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001359
Study accessionGCST000392