Human SNP ID | rs3824999 |
---|---|
Human chromosome | chr11 |
Human SNP position | 74634505 |
Pig chromosome | chr9 |
Pig SNP position | 9788156 |
PubMed ID | 22634755 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22634755 |
Study | Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. |
Disease/Trait | Colorectal cancer |
Initial sample | 8,323 European ancestry cases, 9,457 European ancestry controls |
Replication sample | 19,513 European ancestry cases, 17,657 European ancestry controls, 1,583 Japanese ancestry cases, 1,898 Japanese ancestry controls |
Region | 11q13.4 |
Chromosome id | chr11 |
Chromosome position | 74634505 |
Reported gene | POLD3 |
Mapped gene | POLD3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10714 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3824999-? |
SNPs | rs3824999 |
Merged | 0 |
SNP id current | 3824999 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000000004 |
Pvalue mlog | 9.39794000867203 |
P value text | |
Or beta | 1.08 |
%95 Ci | [1.05-1.10] |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST001544 |
PubMed ID | 25990418 |
Journal | Sci Rep |
Link | www.ncbi.nlm.nih.gov/pubmed/25990418 |
Study | A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. |
Disease/Trait | Colorectal cancer |
Initial sample | 7,577 European ancestry cases, 9,979 European ancestry controls |
Replication sample | NA |
Region | 11q13.4 |
Chromosome id | chr11 |
Chromosome position | 74634505 |
Reported gene | POLD3 |
Mapped gene | POLD3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10714 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3824999-C |
SNPs | rs3824999 |
Merged | 0 |
SNP id current | 3824999 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 0.00000000008 |
Pvalue mlog | 10.096910013008 |
P value text | |
Or beta | 1.15 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [~ 10000000] (imputed) |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST002919 |
PubMed ID | 26151821 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/26151821 |
Study | Genome-wide association study of colorectal cancer identifies six new susceptibility loci. |
Disease/Trait | Colorectal cancer |
Initial sample | 18,299 European ancestry cases, 19,656 European ancestry controls |
Replication sample | 4,725 East Asian ancestry cases, 9,969 East Asian ancestry controls |
Region | 11q13.4 |
Chromosome id | chr11 |
Chromosome position | 74634505 |
Reported gene | POLD3 |
Mapped gene | POLD3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10714 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3824999-G |
SNPs | rs3824999 |
Merged | 0 |
SNP id current | 3824999 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.53 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | |
Or beta | 1.0752687 |
%95 Ci | [1.05-1.1] |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST003017 |