Human SNP ID | rs3824662 |
---|---|
Human chromosome | chr10 |
Human SNP position | 8062245 |
Pig chromosome | chr10 |
Pig SNP position | 69594822 |
PubMed ID | 23996088 |
---|---|
Journal | Blood |
Link | www.ncbi.nlm.nih.gov/pubmed/23996088 |
Study | Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. |
Disease/Trait | Acute lymphoblastic leukemia (B-cell precursor) |
Initial sample | 1,658 European ancestry child cases, 4,723 European ancestry controls |
Replication sample | 1,449 European ancestry child cases, 1,488 European ancestry controls |
Region | 10p14 |
Chromosome id | chr10 |
Chromosome position | 8062245 |
Reported gene | GATA3 |
Mapped gene | GATA3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2625 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3824662-T |
SNPs | rs3824662 |
Merged | 0 |
SNP id current | 3824662 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.17 |
P value | 0.000000000009 |
Pvalue mlog | 11.0457574905606 |
P value text | |
Or beta | 1.31 |
%95 Ci | [1.21-1.41] |
Platform | Illumina [382776] (imputed) |
CNV | N |
Mapped trait | B-cell acute lymphoblastic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000094 |
Study accession | GCST002158 |
PubMed ID | 25468567 |
Journal | Blood |
Link | www.ncbi.nlm.nih.gov/pubmed/25468567 |
Study | A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. |
Disease/Trait | Acute lymphoblastic leukemia (adolescents and young adults) |
Initial sample | 99 European ancestry cases, 1,381 European ancestry controls, 15 African American cases, 1,363 African American controls, 76 Hispanic cases, 1,008 Hispanic controls, 118 other ancestry cases, 2,909 other ancestry controls |
Replication sample | 72 European ancestry cases, 3,667 European ancestry controls, 9 African American cases, 1,076 African American controls, 34 Hispanic cases, 501 Hispanic controls, 47 other ancestry cases, 511 other ancestry controls |
Region | 10p14 |
Chromosome id | chr10 |
Chromosome position | 8062245 |
Reported gene | GATA3 |
Mapped gene | GATA3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2625 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3824662-A |
SNPs | rs3824662 |
Merged | 0 |
SNP id current | 3824662 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.2 |
P value | 0.0000000003 |
Pvalue mlog | 9.52287874528033 |
P value text | |
Or beta | 1.77 |
%95 Ci | [1.48-2.12] |
Platform | Affymetrix [635297] |
CNV | N |
Mapped trait | acute lymphoblastic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000220 |
Study accession | GCST002713 |