SNP Detail For rs3822735
1.Mapping Information
Human SNP ID rs3822735
Human chromosome chr5
Human SNP position 35799892
Pig chromosome chr16
Pig SNP position 22086944
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)
Initial sample261 Japanese ancestry cases, 262 Japanese ancestry controls
Replication sampleNA
Region5p13.2
Chromosome idchr5
Chromosome position35799892
Reported geneSPEF2
Mapped geneSPEF2
Upstream gene id
Downstream gene id
SNP gene ids79925
Upstream gene distance
Downstream gene distance
SNP risk allelers3822735-G
SNPsrs3822735
Merged0
SNP id current3822735
Contextintron_variant
Intergenic0
Allele frequency0.752
P value0.000002
Pvalue mlog5.69897000433601
P value text(Dominant model)
Or beta2.062
%95 Ci[1.500-2.834]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to carboplatin, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002004