Human SNP ID | rs3821236 |
---|---|
Human chromosome | chr2 |
Human SNP position | 191038032 |
Pig chromosome | chr15 |
Pig SNP position | 106924810 |
PubMed ID | 19165918 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19165918 |
Study | Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 431 European ancestry cases, 2,155 European ancestry controls |
Replication sample | 447 European ancestry trios, 293 trios |
Region | 2q32.2 |
Chromosome id | chr2 |
Chromosome position | 191038032 |
Reported gene | STAT4 |
Mapped gene | STAT4 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6775 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3821236-? |
SNPs | rs3821236 |
Merged | 0 |
SNP id current | 3821236 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.19 |
P value | 0.00000000008 |
Pvalue mlog | 10.096910013008 |
P value text | |
Or beta | 1.49 |
%95 Ci | [NR] |
Platform | Affymetrix [313238] |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST000216 |
PubMed ID | 21779181 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21779181 |
Study | Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. |
Disease/Trait | Systemic sclerosis |
Initial sample | 2,296 European ancestry cases, 5,172 European ancestry controls |
Replication sample | 3,175 European ancestry cases, 4,210 European ancestry controls |
Region | 2q32.2 |
Chromosome id | chr2 |
Chromosome position | 191038032 |
Reported gene | STAT4 |
Mapped gene | STAT4 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6775 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3821236-? |
SNPs | rs3821236 |
Merged | 0 |
SNP id current | 3821236 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000009 |
Pvalue mlog | 7.04575749056067 |
P value text | (IcSSc) |
Or beta | 1.31 |
%95 Ci | [1.19-1.48] |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | systemic scleroderma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000717 |
Study accession | GCST001160 |
PubMed ID | 20383147 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20383147 |
Study | Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. |
Disease/Trait | Systemic sclerosis |
Initial sample | 2,296 European ancestry cases, 5,171 European ancestry controls |
Replication sample | 2,753 European ancestry cases, 4,569 European ancestry controls |
Region | 2q32.2 |
Chromosome id | chr2 |
Chromosome position | 191038032 |
Reported gene | STAT4 |
Mapped gene | STAT4 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6775 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3821236-A |
SNPs | rs3821236 |
Merged | 0 |
SNP id current | 3821236 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.2 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | |
Or beta | 1.3 |
%95 Ci | [1.19-1.41] |
Platform | Illumina [279621] |
CNV | N |
Mapped trait | systemic scleroderma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000717 |
Study accession | GCST000650 |