SNP Detail For rs3820282
1.Mapping Information
Human SNP ID rs3820282
Human chromosome chr1
Human SNP position 22141722
Pig chromosome chr6
Pig SNP position 74164358
2.Annotation Information
PubMed ID25581431
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25581431
StudyIdentification of six new susceptibility loci for invasive epithelial ovarian cancer.
Disease/TraitEpithelial ovarian cancer
Initial sample4,368 European ancestry cases, 9,123 European ancestry controls,
Replication sample2,462 European ancestry BRCA1 mutation carrier cases, 12,790 European ancestry BRCA1 mutation carrier controls, up to 631 European ancestry BRCA2 mutation carrier cases, 7,580 European ancestry BRCA2 mutation carrier controls, 9,627 European ancestry sero
Region1p36.12
Chromosome idchr1
Chromosome position22141722
Reported geneWNT4
Mapped geneLOC105376845, WNT4
Upstream gene id
Downstream gene id
SNP gene ids105376845, 54361
Upstream gene distance
Downstream gene distance
SNP risk allelers3820282-?
SNPsrs3820282
Merged0
SNP id current3820282
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta1.11
%95 Ci[1.06-1.15]
PlatformIllumina [up to 10962898] (imputed)
CNVN
Mapped traitMalignant epithelial tumor of ovary
Mapped trait URIhttp://www.orpha.net/ORDO/Orphanet_398934
Study accessionGCST002748
PubMed ID25581431
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25581431
StudyIdentification of six new susceptibility loci for invasive epithelial ovarian cancer.
Disease/TraitEpithelial ovarian cancer
Initial sample4,368 European ancestry cases, 9,123 European ancestry controls,
Replication sample2,462 European ancestry BRCA1 mutation carrier cases, 12,790 European ancestry BRCA1 mutation carrier controls, up to 631 European ancestry BRCA2 mutation carrier cases, 7,580 European ancestry BRCA2 mutation carrier controls, 9,627 European ancestry sero
Region1p36.12
Chromosome idchr1
Chromosome position22141722
Reported geneWNT4
Mapped geneLOC105376845, WNT4
Upstream gene id
Downstream gene id
SNP gene ids105376845, 54361
Upstream gene distance
Downstream gene distance
SNP risk allelers3820282-?
SNPsrs3820282
Merged0
SNP id current3820282
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000008
Pvalue mlog7.09691001300805
P value text(Serous)
Or beta1.12
%95 Ci[1.07-1.17]
PlatformIllumina [up to 10962898] (imputed)
CNVN
Mapped traitMalignant epithelial tumor of ovary
Mapped trait URIhttp://www.orpha.net/ORDO/Orphanet_398934
Study accessionGCST002748