Human SNP ID | rs3812141 |
---|---|
Human chromosome | chr6 |
Human SNP position | 83524425 |
Pig chromosome | chr1 |
Pig SNP position | 92967743 |
PubMed ID | 26031901 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/26031901 |
Study | Genome-wide association study of leukotriene modifier response in asthma. |
Disease/Trait | Response to zileuton treatment in asthma (FEV1 change interaction) |
Initial sample | 160 European and other ancestry zileuton-treated cases, 144 European and other ancestry placebo-controlled cases |
Replication sample | 149 European and other ancestry zileuton-treated cases, 73 European and other ancestry placebo-controlled cases |
Region | 6q14.2 |
Chromosome id | chr6 |
Chromosome position | 83524425 |
Reported gene | PRSS35 |
Mapped gene | PRSS35 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 167681 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3812141-? |
SNPs | rs3812141 |
Merged | |
SNP id current | 3812141 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000008 |
Pvalue mlog | 6.09691001300805 |
P value text | (Additive model) |
Or beta | 0.5 |
%95 Ci | unit decrease |
Platform | Illumina [542562] |
CNV | N |
Mapped trait | FEV change measurement, response to zileuton, asthma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005921, http://www.ebi.ac.uk/efo/EFO_0007676, http://www.ebi.ac.uk/efo/EFO_0000270 |
Study accession | GCST002951 |