Human SNP ID | rs3807306 |
---|---|
Human chromosome | chr7 |
Human SNP position | 128940626 |
Pig chromosome | chr18 |
Pig SNP position | 20757438 |
PubMed ID | 21156761 |
---|---|
Journal | Ann Rheum Dis |
Link | www.ncbi.nlm.nih.gov/pubmed/21156761 |
Study | A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 1,147 European ancestry ACPA positive RA cases, 774 European ancestry ACPA negative RA cases, 1,079 European ancestry controls |
Replication sample | 887 European ancestry ACPA positive RA cases, 1,218 European ancestry controls |
Region | 7q32.1 |
Chromosome id | chr7 |
Chromosome position | 128940626 |
Reported gene | IRF5 |
Mapped gene | IRF5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3663 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3807306-? |
SNPs | rs3807306 |
Merged | 0 |
SNP id current | 3807306 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | (ACPA-negative RA vs controls) |
Or beta | 1.44 |
%95 Ci | [1.25-1.66] |
Platform | Illumina [1723056] (imputed) |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST000917 |