SNP Detail For rs3807306
1.Mapping Information
Human SNP ID rs3807306
Human chromosome chr7
Human SNP position 128940626
Pig chromosome chr18
Pig SNP position 20757438
2.Annotation Information
PubMed ID21156761
JournalAnn Rheum Dis
Linkwww.ncbi.nlm.nih.gov/pubmed/21156761
StudyA genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
Disease/TraitRheumatoid arthritis
Initial sample1,147 European ancestry ACPA positive RA cases, 774 European ancestry ACPA negative RA cases, 1,079 European ancestry controls
Replication sample887 European ancestry ACPA positive RA cases, 1,218 European ancestry controls
Region7q32.1
Chromosome idchr7
Chromosome position128940626
Reported geneIRF5
Mapped geneIRF5
Upstream gene id
Downstream gene id
SNP gene ids3663
Upstream gene distance
Downstream gene distance
SNP risk allelers3807306-?
SNPsrs3807306
Merged0
SNP id current3807306
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000003
Pvalue mlog6.52287874528033
P value text(ACPA-negative RA vs controls)
Or beta1.44
%95 Ci[1.25-1.66]
PlatformIllumina [1723056] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST000917