SNP Detail For rs3806624
1.Mapping Information
Human SNP ID rs3806624
Human chromosome chr3
Human SNP position 27723132
Pig chromosome chr13
Pig SNP position 15922745
2.Annotation Information
PubMed ID24149102
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/24149102
StudyVariation at 3p24.1 and 6q23.3 influences the risk of Hodgkin__s lymphoma.
Disease/TraitHodgkin__s lymphoma
Initial sample1,465 European ancestry cases, 6,417 European ancestry controls
Replication sample1,071 European ancestry cases, 953 cases, 1,853 controls
Region3p24.1
Chromosome idchr3
Chromosome position27723132
Reported geneEOMES
Mapped geneEOMES - LOC105377007
Upstream gene id8320
Downstream gene id105377007
SNP gene ids
Upstream gene distance417
Downstream gene distance74456
SNP risk allelers3806624-G
SNPsrs3806624
Merged0
SNP id current3806624
Contextupstream_gene_variant
Intergenic1
Allele frequency0.45
P value0.000000000001
Pvalue mlog12
P value text
Or beta1.26
%95 Ci[1.18-1.34]
PlatformIllumina [296129]
CNVN
Mapped traitHodgkins lymphoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000183
Study accessionGCST002237
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region3p24.1
Chromosome idchr3
Chromosome position27723132
Reported geneEOMES
Mapped geneEOMES - LOC105377007
Upstream gene id8320
Downstream gene id105377007
SNP gene ids
Upstream gene distance417
Downstream gene distance74456
SNP risk allelers3806624-G
SNPsrs3806624
Merged0
SNP id current3806624
Contextupstream_gene_variant
Intergenic1
Allele frequency0.56
P value0.000000009
Pvalue mlog8.04575749056067
P value text
Or beta1.08
%95 Ci[1.05-1.11]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region3p24.1
Chromosome idchr3
Chromosome position27723132
Reported geneEOMES
Mapped geneEOMES - LOC105377007
Upstream gene id8320
Downstream gene id105377007
SNP gene ids
Upstream gene distance417
Downstream gene distance74456
SNP risk allelers3806624-G
SNPsrs3806624
Merged0
SNP id current3806624
Contextupstream_gene_variant
Intergenic1
Allele frequency0.46
P value0.00000003
Pvalue mlog7.52287874528033
P value text(EA)
Or beta1.08
%95 Ci[1.05-1.12]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318