SNP Detail For rs3805389
1.Mapping Information
Human SNP ID rs3805389
Human chromosome chr4
Human SNP position 55616583
Pig chromosome chr8
Pig SNP position 58587014
2.Annotation Information
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region4q12
Chromosome idchr4
Chromosome position55616583
Reported geneNMU
Mapped geneNMU
Upstream gene id
Downstream gene id
SNP gene ids10874
Upstream gene distance
Downstream gene distance
SNP risk allelers3805389-A
SNPsrs3805389
Merged0
SNP id current3805389
Contextintron_variant
Intergenic0
Allele frequency0.2784
P value0.00000005
Pvalue mlog7.30102999566398
P value text(EA, women)
Or beta0.0272
%95 Ci[0.017-0.037] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region4q12
Chromosome idchr4
Chromosome position55616583
Reported geneNMU
Mapped geneNMU
Upstream gene id
Downstream gene id
SNP gene ids10874
Upstream gene distance
Downstream gene distance
SNP risk allelers3805389-A
SNPsrs3805389
Merged0
SNP id current3805389
Contextintron_variant
Intergenic0
Allele frequency0.2743
P value0.0000002
Pvalue mlog6.69897000433601
P value text(women)
Or beta0.0254
%95 Ci[0.016-0.035] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782