Human SNP ID | rs378108 |
---|---|
Human chromosome | chr21 |
Human SNP position | 39097594 |
Pig chromosome | chr13 |
Pig SNP position | 212859139 |
PubMed ID | 21743469 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21743469 |
Study | Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. |
Disease/Trait | Ankylosing spondylitis |
Initial sample | 3,023 European ancestry cases, 8,779 European ancestry controls |
Replication sample | 2,111 European ancestry cases, 4,483 European ancestry controls |
Region | 21q22.2 |
Chromosome id | chr21 |
Chromosome position | 39097594 |
Reported gene | intergenic |
Mapped gene | LOC102724740 - PSMG1 |
Upstream gene id | 102724740 |
Downstream gene id | 8624 |
SNP gene ids | |
Upstream gene distance | 78338 |
Downstream gene distance | 77852 |
SNP risk allele | rs378108-G |
SNPs | rs378108 |
Merged | 0 |
SNP id current | 378108 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.48 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [2223620] (imputed) |
CNV | N |
Mapped trait | ankylosing spondylitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003898 |
Study accession | GCST001149 |