SNP Detail For rs378108
1.Mapping Information
Human SNP ID rs378108
Human chromosome chr21
Human SNP position 39097594
Pig chromosome chr13
Pig SNP position 212859139
2.Annotation Information
PubMed ID21743469
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21743469
StudyInteraction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.
Disease/TraitAnkylosing spondylitis
Initial sample3,023 European ancestry cases, 8,779 European ancestry controls
Replication sample2,111 European ancestry cases, 4,483 European ancestry controls
Region21q22.2
Chromosome idchr21
Chromosome position39097594
Reported geneintergenic
Mapped geneLOC102724740 - PSMG1
Upstream gene id102724740
Downstream gene id8624
SNP gene ids
Upstream gene distance78338
Downstream gene distance77852
SNP risk allelers378108-G
SNPsrs378108
Merged0
SNP id current378108
Contextregulatory_region_variant
Intergenic1
Allele frequency0.48
P value0.00000000002
Pvalue mlog10.698970004336
P value text
Or beta
%95 Ci
PlatformIllumina [2223620] (imputed)
CNVN
Mapped traitankylosing spondylitis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003898
Study accessionGCST001149