SNP Detail For rs3752246
1.Mapping Information
Human SNP ID rs3752246
Human chromosome chr19
Human SNP position 1056493
Pig chromosome chr2
Pig SNP position 77633928
2.Annotation Information
PubMed ID21460841
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21460841
StudyCommon variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer__s disease.
Disease/TraitAlzheimer__s disease (late onset)
Initial sample8,309 European ancestry cases, 7,366 European ancestry controls
Replication sample10,523 European ancestry cases, 28,231 European ancestry controls
Region19p13.3
Chromosome idchr19
Chromosome position1056493
Reported geneABCA7
Mapped geneABCA7
Upstream gene id
Downstream gene id
SNP gene ids10347
Upstream gene distance
Downstream gene distance
SNP risk allelers3752246-G
SNPsrs3752246
Merged0
SNP id current3752246
Contextmissense_variant
Intergenic0
Allele frequency0.19
P value0.0000006
Pvalue mlog6.22184874961635
P value text
Or beta1.15
%95 Ci[1.09-1.21]
PlatformAffymetrix, Illumina [2324889] (imputed)
CNVN
Mapped traitAlzheimers disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000249
Study accessionGCST001026