SNP Detail For rs374810
1.Mapping Information
Human SNP ID rs374810
Human chromosome chr8
Human SNP position 108083801
Pig chromosome chr4
Pig SNP position 31802723
2.Annotation Information
PubMed ID25064007
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25064007
StudyA genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine.
Disease/TraitOssification of the posterior longitudinal ligament of the spine
Initial sample1,112 Japanese ancestry cases, 6,810 Japanese ancestry controls
Replication sample548 Japanese ancestry cases, 6,469 Japanese ancestry controls
Region8q23.1
Chromosome idchr8
Chromosome position108083801
Reported geneRSPO2, EMC2, EIF3E
Mapped geneRSPO2 - AURKBPS1
Upstream gene id340419
Downstream gene id644233
SNP gene ids
Upstream gene distance116
Downstream gene distance47161
SNP risk allelers374810-G
SNPsrs374810
Merged0
SNP id current374810
Contextupstream_gene_variant
Intergenic1
Allele frequency0.611
P value0.0000000000002
Pvalue mlog12.698970004336
P value text
Or beta1.34
%95 Ci[1.24-1.44]
PlatformIllumina [5163786] (imputed)
CNVN
Mapped traitossification of the posterior longitudinal ligament of the spine
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005895
Study accessionGCST002545