SNP Detail For rs3747517
1.Mapping Information
Human SNP ID rs3747517
Human chromosome chr2
Human SNP position 162272314
Pig chromosome chr15
Pig SNP position 76427542
2.Annotation Information
PubMed ID25903422
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25903422
StudyGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
Disease/TraitPsoriasis
Initial sample3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls
Replication sample5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls
Region2q24.2
Chromosome idchr2
Chromosome position162272314
Reported geneIFIH1
Mapped geneIFIH1
Upstream gene id
Downstream gene id
SNP gene ids64135
Upstream gene distance
Downstream gene distance
SNP risk allelers3747517-T
SNPsrs3747517
Merged0
SNP id current3747517
Contextmissense_variant
Intergenic0
Allele frequency0.274
P value0.00000000003
Pvalue mlog10.5228787452803
P value text(EA, conditional on rs1990760)
Or beta1.33
%95 Ci[1.23-1.45]
PlatformIllumina [up to 4778154] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002874
PubMed ID25903422
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25903422
StudyGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
Disease/TraitPsoriasis
Initial sample3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls
Replication sample5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls
Region2q24.2
Chromosome idchr2
Chromosome position162272314
Reported geneIFIH1
Mapped geneIFIH1
Upstream gene id
Downstream gene id
SNP gene ids64135
Upstream gene distance
Downstream gene distance
SNP risk allelers3747517-T
SNPsrs3747517
Merged0
SNP id current3747517
Contextmissense_variant
Intergenic0
Allele frequency0.274
P value0.000000000000000001
Pvalue mlog18
P value text(conditional on rs1990760)
Or beta1.3
%95 Ci[1.22-1.37]
PlatformIllumina [up to 4778154] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002874