SNP Detail For rs3745571
1.Mapping Information
Human SNP ID rs3745571
Human chromosome chr19
Human SNP position 6475602
Pig chromosome chr2
Pig SNP position 73053988
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)
Initial sample168 Japanese ancestry cases, 335 Japanese ancestry controls
Replication sampleNA
Region19p13.3
Chromosome idchr19
Chromosome position6475602
Reported geneDENND1C
Mapped geneDENND1C
Upstream gene id
Downstream gene id
SNP gene ids79958
Upstream gene distance
Downstream gene distance
SNP risk allelers3745571-T
SNPsrs3745571
Merged0
SNP id current3745571
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.67
P value0.000008
Pvalue mlog5.09691001300805
P value text(Dominant model)
Or beta1.73
%95 Ci[1.276-2.345]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to cyclophosphamide, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_1902518, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002002