Human SNP ID | rs3736830 |
---|---|
Human chromosome | chr13 |
Human SNP position | 49732085 |
Pig chromosome | chr11 |
Pig SNP position | 18098847 |
PubMed ID | 22267201 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22267201 |
Study | Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. |
Disease/Trait | Menopause (age at onset) |
Initial sample | 38,968 European ancestry female individuals |
Replication sample | Up to 14,435 European ancestry female individuals |
Region | 13q14.2 |
Chromosome id | chr13 |
Chromosome position | 49732085 |
Reported gene | KPNA3 |
Mapped gene | KPNA3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3839 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3736830-G |
SNPs | rs3736830 |
Merged | 0 |
SNP id current | 3736830 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.157 |
P value | 0.00000009 |
Pvalue mlog | 7.04575749056067 |
P value text | |
Or beta | 0.18 |
%95 Ci | [0.11-0.25] years decrease |
Platform | Affymetrix, Illumina [2551160] (imputed) |
CNV | N |
Mapped trait | age at menopause |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004704 |
Study accession | GCST001381 |
PubMed ID | 25574825 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25574825 |
Study | Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms. |
Disease/Trait | Inflammatory skin disease |
Initial sample | 2,079 European ancestry atopic dermatitis cases, 4,212 European ancestry psoriasis cases, 11,899 European ancestry controls |
Replication sample | NA |
Region | 13q14.2 |
Chromosome id | chr13 |
Chromosome position | 49732085 |
Reported gene | KPNA3 |
Mapped gene | KPNA3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3839 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3736830-? |
SNPs | rs3736830 |
Merged | 0 |
SNP id current | 3736830 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | (Shared) |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 5200000] |
CNV | N |
Mapped trait | atopic eczema, psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000274, http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002740 |