Human SNP ID | rs3734729 |
---|---|
Human chromosome | chr6 |
Human SNP position | 150249731 |
Pig chromosome | chr1 |
Pig SNP position | 17996225 |
PubMed ID | 21946350 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21946350 |
Study | Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. |
Disease/Trait | Pulmonary function |
Initial sample | 48,201 European ancestry individuals |
Replication sample | 46,411 European ancestry individuals |
Region | 6q25.1 |
Chromosome id | chr6 |
Chromosome position | 150249731 |
Reported gene | PPP1R14C |
Mapped gene | PPP1R14C |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 81706 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3734729-G |
SNPs | rs3734729 |
Merged | 0 |
SNP id current | 3734729 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (FEV1) |
Or beta | 0.055 |
%95 Ci | [0.031-0.079] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | pulmonary function measurement, forced expiratory volume |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004314 |
Study accession | GCST001251 |
PubMed ID | 23284291 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23284291 |
Study | Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. |
Disease/Trait | Pulmonary function (interaction) |
Initial sample | 50,047 European ancestry individuals |
Replication sample | NA |
Region | 6q25.1 |
Chromosome id | chr6 |
Chromosome position | 150249731 |
Reported gene | PPP1R1 |
Mapped gene | PPP1R14C |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 81706 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3734729-A |
SNPs | rs3734729 |
Merged | 0 |
SNP id current | 3734729 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | (FEV1, Ever-smoking) |
Or beta | |
%95 Ci | |
Platform | NR [~ 2500000] (imputed) |
CNV | N |
Mapped trait | forced expiratory volume |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004314 |
Study accession | GCST001784 |
PubMed ID | 23284291 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23284291 |
Study | Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. |
Disease/Trait | Pulmonary function (interaction) |
Initial sample | 50,047 European ancestry individuals |
Replication sample | NA |
Region | 6q25.1 |
Chromosome id | chr6 |
Chromosome position | 150249731 |
Reported gene | PPP1R1 |
Mapped gene | PPP1R14C |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 81706 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs3734729-A |
SNPs | rs3734729 |
Merged | 0 |
SNP id current | 3734729 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000007 |
Pvalue mlog | 6.15490195998574 |
P value text | (FEV1, Pack-years) |
Or beta | |
%95 Ci | |
Platform | NR [~ 2500000] (imputed) |
CNV | N |
Mapped trait | forced expiratory volume |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004314 |
Study accession | GCST001784 |