Human SNP ID | rs365990 |
---|---|
Human chromosome | chr14 |
Human SNP position | 23392602 |
Pig chromosome | chr7 |
Pig SNP position | 81048305 |
PubMed ID | 20062063 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20062063 |
Study | Several common variants modulate heart rate, PR interval and QRS duration. |
Disease/Trait | Electrocardiographic traits |
Initial sample | Up to 12,670 European ancestry individuals |
Replication sample | Up to 10,352 European ancestry individuals |
Region | 14q11.2 |
Chromosome id | chr14 |
Chromosome position | 23392602 |
Reported gene | MYH6 |
Mapped gene | MYH6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4624 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs365990-G |
SNPs | rs365990 |
Merged | 0 |
SNP id current | 365990 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.34 |
P value | 0.00000000009 |
Pvalue mlog | 10.0457574905606 |
P value text | (HR) |
Or beta | 5.25 |
%95 Ci | [3.66-6.83] % s.d. increase |
Platform | Illumina [306060] |
CNV | N |
Mapped trait | heart rate |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004326 |
Study accession | GCST000561 |
PubMed ID | 23583979 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23583979 |
Study | Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. |
Disease/Trait | Heart rate |
Initial sample | 85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals |
Replication sample | 88,823 European ancestry individuals |
Region | 14q11.2 |
Chromosome id | chr14 |
Chromosome position | 23392602 |
Reported gene | MYH6 |
Mapped gene | MYH6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4624 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs365990-G |
SNPs | rs365990 |
Merged | 0 |
SNP id current | 365990 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.353 |
P value | 5E-45 |
Pvalue mlog | 44.3010299956639 |
P value text | |
Or beta | 0.564 |
%95 Ci | [0.47-0.66] unit increase |
Platform | Affymetrix, Illumina [2516789] (imputed) |
CNV | N |
Mapped trait | heart rate |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004326 |
Study accession | GCST001969 |