SNP Detail For rs36056951
1.Mapping Information
Human SNP ID rs36056951
Human chromosome chr8
Human SNP position 138953555
Pig chromosome chr4
Pig SNP position 3802653
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCerebrospinal T-tau levels
Initial sampleup to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer__s disease cases, up to 215 European and other ance
Replication sampleup to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other an
Region8q24.3
Chromosome idchr8
Chromosome position138953555
Reported geneCOL22A1, KCNK9
Mapped geneCOL22A1 - KCNK9
Upstream gene id169044
Downstream gene id51305
SNP gene ids
Upstream gene distance39461
Downstream gene distance647283
SNP risk allelers36056951-C
SNPsrs36056951
Merged
SNP id current36056951
Contextintergenic_variant
Intergenic1
Allele frequency0.03
P value0.0000004
Pvalue mlog6.39794000867203
P value text
Or beta0.3291
%95 Ci[NR] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcerebrospinal fluid biomarker measurement, t-tau measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006794, http://www.ebi.ac.uk/efo/EFO_0004760
Study accessionGCST003070
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCerebrospinal fluid t-tau:AB1-42 ratio
Initial sampleup to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer__s disease cases, up to 215 European and other ance
Replication sampleup to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other an
Region8q24.3
Chromosome idchr8
Chromosome position138953555
Reported geneCOL22A1, KCNK9
Mapped geneCOL22A1 - KCNK9
Upstream gene id169044
Downstream gene id51305
SNP gene ids
Upstream gene distance39461
Downstream gene distance647283
SNP risk allelers36056951-C
SNPsrs36056951
Merged
SNP id current36056951
Contextintergenic_variant
Intergenic1
Allele frequency0.03
P value0.000004
Pvalue mlog5.39794000867203
P value text
Or beta0.3732
%95 Ci[NR] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitt-tau:beta-amyloid 1-42 ratio measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0007708
Study accessionGCST003079