SNP Detail For rs35053544
1.Mapping Information
Human SNP ID rs35053544
Human chromosome chr15
Human SNP position 45830738
Pig chromosome chr1
Pig SNP position 140601116
2.Annotation Information
PubMed ID24159190
JournalEur Heart J
Linkwww.ncbi.nlm.nih.gov/pubmed/24159190
StudyGenome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
Disease/TraitSerum dimethylarginine levels (asymmetric/symetric ratio)
Initial sample5110 European ancestry individuals
Replication sampleNA
Region15q21.1
Chromosome idchr15
Chromosome position45830738
Reported geneNR
Mapped geneSQRDL - LOC105370802
Upstream gene id58472
Downstream gene id105370802
SNP gene ids
Upstream gene distance139444
Downstream gene distance96091
SNP risk allelers35053544-C
SNPsrs35053544
Merged0
SNP id current35053544
Contextintron_variant
Intergenic1
Allele frequency0.075
P value0.0000008
Pvalue mlog6.09691001300805
P value text
Or beta0.189
%95 Ci[0.11-0.26] unit decrease
PlatformAffymetrix, Illumina [10085758] (imputed)
CNVN
Mapped traitserum dimethylarginine measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005418
Study accessionGCST002242
PubMed ID24159190
JournalEur Heart J
Linkwww.ncbi.nlm.nih.gov/pubmed/24159190
StudyGenome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
Disease/TraitSymmetrical dimethylarginine levels
Initial sample5110 European ancestry individuals
Replication sampleNA
Region15q21.1
Chromosome idchr15
Chromosome position45830738
Reported geneNR
Mapped geneSQRDL - LOC105370802
Upstream gene id58472
Downstream gene id105370802
SNP gene ids
Upstream gene distance139444
Downstream gene distance96091
SNP risk allelers35053544-C
SNPsrs35053544
Merged0
SNP id current35053544
Contextintron_variant
Intergenic1
Allele frequency0.076
P value0.000006
Pvalue mlog5.22184874961635
P value text
Or beta0.173
%95 Ci[0.099-0.247] unit increase
PlatformAffymetrix, Illumina [10085758] (imputed)
CNVN
Mapped traitserum dimethylarginine measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005418
Study accessionGCST002239