SNP Detail For rs34670419
1.Mapping Information
Human SNP ID rs34670419
Human chromosome chr7
Human SNP position 99533211
Pig chromosome chr3
Pig SNP position 6589273
2.Annotation Information
PubMed ID26014426
JournalEur J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26014426
StudyGenome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes.
Disease/TraitSex hormone levels
Initial sampleup to 2913 European ancestry individuals
Replication sampleNA
Region7q22.1
Chromosome idchr7
Chromosome position99533211
Reported geneZKSCAN5, CYP3A4, CYP3A7
Mapped geneZKSCAN5
Upstream gene id
Downstream gene id
SNP gene ids23660
Upstream gene distance
Downstream gene distance
SNP risk allelers34670419-T
SNPsrs34670419
Merged0
SNP id current34670419
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.037
P value0.00000000000006
Pvalue mlog13.2218487496163
P value text(Progesterone)
Or beta0.346
%95 Ci[NR] unit decrease
PlatformIllumina [7879351] (imputed)
CNVN
Mapped traithormone measurement, progesterone measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004730, http://www.ebi.ac.uk/efo/EFO_0007004
Study accessionGCST002925
PubMed ID26014426
JournalEur J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26014426
StudyGenome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes.
Disease/TraitSex hormone levels
Initial sampleup to 2913 European ancestry individuals
Replication sampleNA
Region7q22.1
Chromosome idchr7
Chromosome position99533211
Reported geneZKSCAN5, CYP3A4, CYP3A7
Mapped geneZKSCAN5
Upstream gene id
Downstream gene id
SNP gene ids23660
Upstream gene distance
Downstream gene distance
SNP risk allelers34670419-T
SNPsrs34670419
Merged0
SNP id current34670419
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.037
P value0.00000000000002
Pvalue mlog13.698970004336
P value text(DHEAS)
Or beta0.259
%95 Ci[NR] unit decrease
PlatformIllumina [7879351] (imputed)
CNVN
Mapped traithormone measurement, dehydroepiandrosterone sulphate measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004730, http://www.ebi.ac.uk/efo/EFO_0007001
Study accessionGCST002925
PubMed ID26014426
JournalEur J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26014426
StudyGenome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes.
Disease/TraitSex hormone levels
Initial sampleup to 2913 European ancestry individuals
Replication sampleNA
Region7q22.1
Chromosome idchr7
Chromosome position99533211
Reported geneZKSCAN5, CYP3A4, CYP3A7
Mapped geneZKSCAN5
Upstream gene id
Downstream gene id
SNP gene ids23660
Upstream gene distance
Downstream gene distance
SNP risk allelers34670419-T
SNPsrs34670419
Merged0
SNP id current34670419
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.037
P value0.0000002
Pvalue mlog6.69897000433601
P value text(Testosterone)
Or beta0.213
%95 Ci[NR] unit decrease
PlatformIllumina [7879351] (imputed)
CNVN
Mapped traithormone measurement, testosterone measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004730, http://www.ebi.ac.uk/efo/EFO_0004908
Study accessionGCST002925