SNP Detail For rs34395537
1.Mapping Information
Human SNP ID rs34395537
Human chromosome chr2
Human SNP position 183628013
Pig chromosome chr15
Pig SNP position 98770638
2.Annotation Information
PubMed ID26053186
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26053186
StudyMercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
Disease/Trait3-hydroxypropylmercapturic acid levels in smokers
Initial sample362 African American current smoker individuals, 329 Native Hawaiian ancestry current smoker individuals, 438 European ancestry current smoker individuals, 449 Latino current smoker individuals, 704 Japanese ancestry current smoker individuals
Replication sampleNA
Region2q32.1
Chromosome idchr2
Chromosome position183628013
Reported geneNR
Mapped geneLOC105373774 - LOC105373775
Upstream gene id105373774
Downstream gene id105373775
SNP gene ids
Upstream gene distance412613
Downstream gene distance421127
SNP risk allelers34395537-?
SNPsrs34395537
Merged
SNP id current34395537
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000000008
Pvalue mlog9.09691001300805
P value text(Latino)
Or beta1.7295
%95 Ci[NR] unit decrease
PlatformIllumina [up to 11892802] (imputed)
CNVN
Mapped traitsmoking behavior, 3-hydroxypropylmercapturic acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007014
Study accessionGCST002956
PubMed ID26053186
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26053186
StudyMercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
Disease/Trait3-hydroxy-1-methylpropylmercapturic acid levels in smokers
Initial sample361 African American current smoker individuals, 329 Native Hawaiian ancestry current smoker individuals, 440 European ancestry current smoker individuals, 452 Latino current smoker individuals, 702 Japanese ancestry current smoker individuals
Replication sampleNA
Region2q32.1
Chromosome idchr2
Chromosome position183628013
Reported geneNR
Mapped geneLOC105373774 - LOC105373775
Upstream gene id105373774
Downstream gene id105373775
SNP gene ids
Upstream gene distance412613
Downstream gene distance421127
SNP risk allelers34395537-?
SNPsrs34395537
Merged
SNP id current34395537
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000003
Pvalue mlog6.52287874528033
P value text(Latino)
Or beta1.3226
%95 Ci[NR] unit decrease
PlatformIllumina [up to 11892802] (imputed)
CNVN
Mapped traitsmoking behavior, 3-hydroxy-1-methylpropylmercapturic acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007015
Study accessionGCST002957