Human SNP ID | rs33980500 |
---|---|
Human chromosome | chr6 |
Human SNP position | 111592059 |
Pig chromosome | chr1 |
Pig SNP position | 87084665 |
PubMed ID | 20953186 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20953186 |
Study | Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. |
Disease/Trait | Psoriatic arthritis |
Initial sample | 572 European ancestry cases, 888 European ancestry controls |
Replication sample | Up to 1,761 European ancestry cases, 3,727 European ancestry controls |
Region | 6q21 |
Chromosome id | chr6 |
Chromosome position | 111592059 |
Reported gene | TRAF3IP2 |
Mapped gene | TRAF3IP2-AS1, TRAF3IP2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 643749, 10758 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs33980500-T |
SNPs | rs33980500 |
Merged | 0 |
SNP id current | 33980500 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.07 |
P value | 1E-20 |
Pvalue mlog | 20 |
P value text | |
Or beta | 1.95 |
%95 Ci | [1.69-2.24] |
Platform | Affymetrix [1585307] (imputed) |
CNV | N |
Mapped trait | psoriatic arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003778 |
Study accession | GCST000835 |
PubMed ID | 20953188 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20953188 |
Study | Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. |
Disease/Trait | Psoriasis |
Initial sample | 472 European ancestry cases, 1,146 European ancestry controls |
Replication sample | 2,668, European ancestry cases, 762 French Canadian founder population cases, 2,585 cases, 3,485 European ancestry controls, 994 French Canadian founder population controls, 2,412 controls |
Region | 6q21 |
Chromosome id | chr6 |
Chromosome position | 111592059 |
Reported gene | TRAF3IP2 |
Mapped gene | TRAF3IP2-AS1, TRAF3IP2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 643749, 10758 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs33980500-T |
SNPs | rs33980500 |
Merged | 0 |
SNP id current | 33980500 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.08 |
P value | 0.0000000000000001 |
Pvalue mlog | 16 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [2339118] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST000836 |
PubMed ID | 26626624 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26626624 |
Study | Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. |
Disease/Trait | Psoriasis vulgaris |
Initial sample | 4,007 European ancestry cases, 4,934 European ancestry controls |
Replication sample | up to 9,075 European ancestry cases, up to European ancestry 12,726 controls |
Region | 6q21 |
Chromosome id | chr6 |
Chromosome position | 111592059 |
Reported gene | TRAF3IP2 |
Mapped gene | TRAF3IP2-AS1, TRAF3IP2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 643749, 10758 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs33980500-T |
SNPs | rs33980500 |
Merged | 0 |
SNP id current | 33980500 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 1E-23 |
Pvalue mlog | 23 |
P value text | |
Or beta | 1.44 |
%95 Ci | NR |
Platform | Illumina [up to 11532644] (imputed) |
CNV | N |
Mapped trait | |
Mapped trait URI | |
Study accession | GCST003268 |
PubMed ID | 26626624 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26626624 |
Study | Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. |
Disease/Trait | Psoriatic arthritis |
Initial sample | 1,946 European ancestry cases, 4,934 European ancestry controls |
Replication sample | up to 2,883 European ancestry cases, up to 14,179 European ancestry controls |
Region | 6q21 |
Chromosome id | chr6 |
Chromosome position | 111592059 |
Reported gene | TRAF3IP2 |
Mapped gene | TRAF3IP2-AS1, TRAF3IP2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 643749, 10758 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs33980500-T |
SNPs | rs33980500 |
Merged | 0 |
SNP id current | 33980500 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000000000000001 |
Pvalue mlog | 17 |
P value text | |
Or beta | 1.599 |
%95 Ci | NR |
Platform | Illumina [11532644] (imputed) |
CNV | N |
Mapped trait | psoriatic arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003778 |
Study accession | GCST003270 |