SNP Detail For rs331463
1.Mapping Information
Human SNP ID rs331463
Human chromosome chr11
Human SNP position 36480237
Pig chromosome chr2
Pig SNP position 26794490
2.Annotation Information
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region11p12
Chromosome idchr11
Chromosome position36480237
Reported geneTRAF6, RAG1, RAG2
Mapped genePRR5L - TRAF6
Upstream gene id79899
Downstream gene id7189
SNP gene ids
Upstream gene distance15033
Downstream gene distance3530
SNP risk allelers331463-T
SNPsrs331463
Merged0
SNP id current331463
Contextintergenic_variant
Intergenic1
Allele frequency0.85
P value0.0000001
Pvalue mlog7
P value text(EA)
Or beta1.12
%95 Ci[1.07-1.16]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region11p12
Chromosome idchr11
Chromosome position36480237
Reported geneTRAF6, RAG1, RAG2
Mapped genePRR5L - TRAF6
Upstream gene id79899
Downstream gene id7189
SNP gene ids
Upstream gene distance15033
Downstream gene distance3530
SNP risk allelers331463-T
SNPsrs331463
Merged0
SNP id current331463
Contextintergenic_variant
Intergenic1
Allele frequency0.87
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta1.1
%95 Ci[1.06-1.14]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318