SNP Detail For rs3218251
1.Mapping Information
Human SNP ID rs3218251
Human chromosome chr22
Human SNP position 37149465
Pig chromosome chr5
Pig SNP position 8224554
2.Annotation Information
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region22q12.3
Chromosome idchr22
Chromosome position37149465
Reported geneIL2RB
Mapped geneIL2RB
Upstream gene id
Downstream gene id
SNP gene ids3560
Upstream gene distance
Downstream gene distance
SNP risk allelers3218251-A
SNPsrs3218251
Merged0
SNP id current3218251
Contextintron_variant
Intergenic0
Allele frequency0.27
P value0.000006
Pvalue mlog5.22184874961635
P value text(EA)
Or beta1.08
%95 Ci[1.04-1.11]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318