Human SNP ID | rs314277 |
---|---|
Human chromosome | chr6 |
Human SNP position | 104959787 |
Pig chromosome | chr1 |
Pig SNP position | 80447203 |
PubMed ID | 19448621 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19448621 |
Study | Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. |
Disease/Trait | Menarche and menopause (age at onset) |
Initial sample | 17,438 European ancestry female individuals |
Replication sample | NA |
Region | 6q16.3 |
Chromosome id | chr6 |
Chromosome position | 104959787 |
Reported gene | LIN28B |
Mapped gene | LIN28B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 389421 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs314277-A |
SNPs | rs314277 |
Merged | 0 |
SNP id current | 314277 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.14 |
P value | 0.0000000000003 |
Pvalue mlog | 12.5228787452803 |
P value text | (age at menarche) |
Or beta | 0.16 |
%95 Ci | [0.12-0.20] years increase |
Platform | Illumina [317759] |
CNV | N |
Mapped trait | age at menarche |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004703 |
Study accession | GCST000403 |
PubMed ID | 20303062 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20303062 |
Study | A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. |
Disease/Trait | Digit length ratio |
Initial sample | 2,889 European ancestry children and adolescents |
Replication sample | 3,659 European ancestry children |
Region | 6q16.3 |
Chromosome id | chr6 |
Chromosome position | 104959787 |
Reported gene | LIN28B |
Mapped gene | LIN28B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 389421 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs314277-A |
SNPs | rs314277 |
Merged | 0 |
SNP id current | 314277 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.15 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | |
Or beta | 0.63 |
%95 Ci | [0.41-0.85] mean 2D:4D increase |
Platform | Illumina [310613] |
CNV | N |
Mapped trait | digit length ratio |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004841 |
Study accession | GCST000630 |
PubMed ID | 18391950 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18391950 |
Study | Identification of ten loci associated with height highlights new biological pathways in human growth. |
Disease/Trait | Height |
Initial sample | 15,821 European ancestry individuals |
Replication sample | Up to 17,801 European ancestry individuals |
Region | 6q16.3 |
Chromosome id | chr6 |
Chromosome position | 104959787 |
Reported gene | LIN28B |
Mapped gene | LIN28B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 389421 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs314277-A |
SNPs | rs314277 |
Merged | 0 |
SNP id current | 314277 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.13 |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | |
Or beta | 0.41 |
%95 Ci | [0.26-0.59] cm increase |
Platform | Affymetrix, Illumina [2260683] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST000176 |